Search details
1.
Pre-mRNA splicing factor U2AF2 recognizes distinct conformations of nucleotide variants at the center of the pre-mRNA splice site signal.
Nucleic Acids Res
; 50(9): 5299-5312, 2022 05 20.
Article
in English
| MEDLINE | ID: mdl-35524551
2.
A UHM-ULM interface with unusual structural features contributes to U2AF2 and SF3B1 association for pre-mRNA splicing.
J Biol Chem
; 298(8): 102224, 2022 08.
Article
in English
| MEDLINE | ID: mdl-35780835
3.
A splice site-sensing conformational switch in U2AF2 is modulated by U2AF1 and its recurrent myelodysplasia-associated mutation.
Nucleic Acids Res
; 48(10): 5695-5709, 2020 06 04.
Article
in English
| MEDLINE | ID: mdl-32343311
4.
Representative cancer-associated U2AF2 mutations alter RNA interactions and splicing.
J Biol Chem
; 295(50): 17148-17157, 2020 12 11.
Article
in English
| MEDLINE | ID: mdl-33020180
5.
Cus2 enforces the first ATP-dependent step of splicing by binding to yeast SF3b1 through a UHM-ULM interaction.
RNA
; 25(8): 1020-1037, 2019 08.
Article
in English
| MEDLINE | ID: mdl-31110137
6.
The pre-mRNA splicing and transcription factor Tat-SF1 is a functional partner of the spliceosome SF3b1 subunit via a U2AF homology motif interface.
J Biol Chem
; 294(8): 2892-2902, 2019 02 22.
Article
in English
| MEDLINE | ID: mdl-30567737
7.
Splicing Factor Mutations in Myelodysplasias: Insights from Spliceosome Structures.
Trends Genet
; 33(5): 336-348, 2017 05.
Article
in English
| MEDLINE | ID: mdl-28372848
8.
Dynamic stacking of an expected branch point adenosine in duplexes containing pseudouridine-modified or unmodified U2 snRNA sites.
Biochem Biophys Res Commun
; 511(2): 416-421, 2019 04 02.
Article
in English
| MEDLINE | ID: mdl-30797552
9.
Wild-Type U2AF1 Antagonizes the Splicing Program Characteristic of U2AF1-Mutant Tumors and Is Required for Cell Survival.
PLoS Genet
; 12(10): e1006384, 2016 Oct.
Article
in English
| MEDLINE | ID: mdl-27776121
10.
Unmasking the U2AF homology motif family: a bona fide protein-protein interaction motif in disguise.
RNA
; 22(12): 1795-1807, 2016 12.
Article
in English
| MEDLINE | ID: mdl-27852923
11.
Structural basis for NADH/NAD+ redox sensing by a Rex family repressor.
Mol Cell
; 38(4): 563-75, 2010 May 28.
Article
in English
| MEDLINE | ID: mdl-20513431
12.
Cancer-Associated Mutations Mapped on High-Resolution Structures of the U2AF2 RNA Recognition Motifs.
Biochemistry
; 56(36): 4757-4761, 2017 09 12.
Article
in English
| MEDLINE | ID: mdl-28850223
13.
Structure-guided U2AF65 variant improves recognition and splicing of a defective pre-mRNA.
Proc Natl Acad Sci U S A
; 111(49): 17420-5, 2014 Dec 09.
Article
in English
| MEDLINE | ID: mdl-25422459
14.
SF1 Phosphorylation Enhances Specific Binding to U2AF65 and Reduces Binding to 3'-Splice-Site RNA.
Biophys J
; 111(12): 2570-2586, 2016 Dec 20.
Article
in English
| MEDLINE | ID: mdl-28002734
15.
Cancer-relevant splicing factor CAPERα engages the essential splicing factor SF3b155 in a specific ternary complex.
J Biol Chem
; 289(25): 17325-37, 2014 Jun 20.
Article
in English
| MEDLINE | ID: mdl-24795046
16.
U2AF65 adapts to diverse pre-mRNA splice sites through conformational selection of specific and promiscuous RNA recognition motifs.
Nucleic Acids Res
; 41(6): 3859-73, 2013 Apr 01.
Article
in English
| MEDLINE | ID: mdl-23376934
17.
A Broad range of conformations contribute to the solution ensemble of the essential splicing factor U2AF(65).
Biochemistry
; 51(26): 5223-5, 2012 Jul 03.
Article
in English
| MEDLINE | ID: mdl-22702716
18.
Large favorable enthalpy changes drive specific RNA recognition by RNA recognition motif proteins.
Biochemistry
; 50(9): 1429-31, 2011 Mar 08.
Article
in English
| MEDLINE | ID: mdl-21261285
19.
Purification, crystallization and preliminary X-ray crystallographic analysis of a central domain of human splicing factor 1.
Acta Crystallogr Sect F Struct Biol Cryst Commun
; 67(Pt 4): 486-90, 2011 Apr 01.
Article
in English
| MEDLINE | ID: mdl-21505248
20.
Sodium Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis of Proteins.
Cold Spring Harb Protoc
; 2021(12)2021 12 01.
Article
in English
| MEDLINE | ID: mdl-34853120